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A 3D human neural cell culture system for modeling Alzheimer's disease
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In this study, the authors descibe a protocol based on the used of lentiviral vectorsto generate a3D human neural cell culture. in 1-2 days for modeling Alzheimer's disease. The aggregation of Aβ is observed after 6 weeks of differentiation, followed by robust tau pathology after 10–14 weeks.
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