In this study, the authors used a lentiviral vector to express MYOD and improve the myogenic differentiation potential of equine adipose-derived stem cells (eqASCs). They tested this strategy in vitro and in vivo by transplantation of transduced cells into the tibialis anterior muscles of mice. Their findings suggest that limitations in the treatment of equine muscle disorders could be overcome using ASCs.
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In this study, the authors used a lentiviral vector to express MYOD and improve the myogenic differentiation potential of equine adipose-derived stem cells (eqASCs). They tested this strategy in vitro and in vivo by transplantation of transduced cells into the tibialis anterior muscles of mice. Their findings suggest that limitations in the treatment of equine muscle disorders could be overcome using ASCs.
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