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Vectorology - GEG Tech top picks
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Virus-like particles (VLPs) derived from retroviruses and lentiviruses can be used to deliver recombinant proteins without the fear of causing insertional mutagenesis to the host cell genome. In this study the scientists evaluate the potential of an inducible lentiviral vector packaging cell line for VLP production. The results demonstrated that their platform produced VLPs capable of efficient protein transfer, and it was shown that protein engineering can be used to improve the activity of the delivered proteins as well as VLP production.